Innovative Health Solutions – Pfizer launches 1Click2Grow website to promote public education and transform health outcomes for children with growth hormone deficiency.
Pfizer is committed to innovations that consistently change patients’ lives. This brand innovates every day to create a healthier world. Pfizer recently created the website 1Click2Grow to promote public knowledge and improve health outcomes for children with growth hormone deficiency.
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Growth hormone deficiency (GHD) is a growth disorder associated with insufficient secretion of growth hormone (GH) from the pituitary gland, the “master gland” of the brain.
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Pfizer is committed to exploring the potential of technological advances to cure disease and significantly improve the lives of patients. 1Click2Grow aims to inform and support parents of children aged 2 to 10 so that they can monitor their child’s growth patterns and identify early warning signs.
Growth is a useful determinant of overall health, and abnormal growth patterns can be a sign of poor health for parents and health professionals. The One Minute Height and Weight Calculator on the newly launched website allows caregivers to visualize how their child’s height and weight compare to the standard growth curve based on the WHO growth chart. This could potentially help caregivers notice if their child’s growth is below average in order to seek professional support. To deliver game-changing medicines and solutions, Pfizer combines cutting-edge science and a deep understanding of how diseases work with insights from creative strategic partnerships with university researchers, patients and other physicians. Let’s better understand GHD, its effects and symptoms.
This is a rare disease that can be caused by genetic mutations or acquired after birth.1 The patient’s pituitary gland secretes enough somatropin, a growth-stimulating hormone, to reduce the patient’s height and delay puberty. Without treatment, the patient will continue to experience stunted growth, very short adult height, and other health problems.
Growth hormone deficiency affects approximately 4,000 to 10,000 people worldwide. It can be congenital (if caused by a genetic mutation) or acquired after birth due to trauma, brain tumors, surgery, or radiation therapy. It can also be idiopathic, where the cause is unknown. In some cases, this can occur when the patient is also deficient in other hormones, including hormones that activate the thyroid and adrenal glands.
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The disorder causes the long bones of the limbs to take longer to mature, causing abnormal growth for the child’s age.
Plotting the results on an appropriate growth chart requires accurate measurements of length (collected from birth to two-year-old patient) or standing height (from two years of age). In all developmental delays, the child’s growth pattern should be continuously monitored and contrasted with typical trends for children of the same age and sex.
If growth retardation is detected, a blood test should be performed to measure the level of growth factor I (IGF-I), the level of which depends on the level of growth hormone. Bone age should also be assessed by X-ray imaging of the patient’s left arm.
A growth hormone stimulation test may be required. This includes measuring growth hormone before and after taking growth hormone-stimulating drugs.
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Treatment involves daily or weekly injections of growth hormone over several years. During this time, the child should visit the doctor regularly to make sure that the medicine is working and that the dose is correct. Older children can learn to give from themselves.
The sooner the condition is treated, the greater the child’s chance of growing to nearly normal height as an adult. Typically, patients grow four inches or more during the first year of treatment, and three or more inches over the next two years. Growth then continued, but at a slower pace.
If the condition is not treated, it can lead to delayed puberty and permanent short stature, as well as other metabolic conditions.
Disclaimer. The content is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your doctor or other qualified professional with any questions regarding your health condition. Do not disregard or delay seeking professional medical advice because of what you read or see in this content. A pocket-sized ultrasound machine that costs 50 seconds less than a hospital machine (and connects to your phone). Virtual reality speeds up rehabilitation. Artificial intelligence is better than medical experts at detecting lung tumors. These are some of the innovations that are currently changing medicine at an incredible speed.
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No one can predict the future, but at least it can be seen in the dozens of inventions and concepts below. Like the people behind them, they are at the forefront of health care. The list is neither exhaustive nor exclusive, but rather represents the transformation of public health and medical science likely to come in the 2020s.
Since March, UPS has been running a test program called Flight Forward, using an autonomous drone to deliver critical medical samples, including blood or tissue, between two hospital branches in Raleigh, N.C., 150 yards apart. The swift-footed runner can cover distances as fast as drones, but as a proof-of-concept project, it worked, and the FAA in October gave the company permission to expand to 20 hospitals in the U.S. over the next two years. years. “We hope that UPS Flight Forward will one day become a very important part of our company,” said UPS CEO David Abney of the service, which will deliver urine, blood and tissue samples, as well as medical needs such as drugs and the blood can be transfused. UPS is not alone in pioneering air delivery. Wing, a division of Google’s parent company Alphabet, has received similar, but more limited, FAA approval to ship to Walgreens and FedEx. And in Ghana and Rwanda, drones operated by Silicon Valley startup Zipline have delivered medical supplies to villages. — Jeffrey Kluger
There are 7.5 billion people, and tens of millions of us monitor our health using wearables like smartwatches as well as traditional devices like blood pressure monitors. If there was a way to collect all that data from even a few million people and make it anonymous yet searchable, medical researchers would have a powerful tool for drug development, lifestyle studies, and more. California-based big data company Evidation developed such a tool, providing trillions of data points with information from 3 million volunteers. Evidation works with drugmakers such as Sanofi and Eli Lilly to analyze that data; that work has already led to dozens of peer-reviewed studies on topics ranging from sleep and nutrition to patterns of cognitive health. Founder Christine Lemke, one of Evidation’s current projects to see if the new technology can effectively measure chronic pain, is personal. Lemke has a rare genetic condition that causes frequent back pain. Evidation is partnering with Brigham and Women’s Hospital on the project.-Jeffrey Kluger
Type 1 diabetes affects 1.25 million Americans, but two in particular caught the attention of Harvard biologist Doug Melton: his daughter Emma and son Sam. Treatment may include a careful diet, insulin injections, and several blood glucose tests per day. Melton takes a different approach, using stem cells to create replacement beta cells that produce insulin. He began his work more than 10 years ago, when stem cell research raised hopes and controversy. In 2014, he co-founded Semma Therapeutics, named after Sam and Emma, to develop the technology, which was acquired by Vertek Pharmaceuticals for $950 million this summer. The company has created a tiny implantable device that contains millions of replacement beta cells, letting glucose and insulin in but keeping immune cells out. “If this works in humans as well as in animals, it’s possible that humans won’t have diabetes,” Melton said. “They will eat, drink and play like the rest of us.” – Don Steinberg
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A major limitation threatens to inhibit the era of personalized medicine. Caucasians are a minority of the world’s population, but nearly 80% of the subjects of human genome research, creating a blind spot in medical research. Dr. Abbasi Ene-Obong, 34, has engineered 54 genes to change that. A Nigerian-based startup named after Africa’s 54 countries is harvesting genetic material from volunteers across the continent to make drug research and development more equitable. 54gen is aware of the ugly history of colonial exploitation in Africa. If a company wants to benefit from developing marketable drugs based on African DNA, Africa must benefit. therefore, when Maskumambang and company, 54gene prioritizes those who have committed to be included in the African country marketing program for any drug received. “If we are part of the way to create drugs, then maybe we can be on the way to bring those drugs to Africa,” Ene-Obong said. – Corinne Purtill
One of the initial disruptions of the new economy is its approach to medical research. The Parker Institute for Cancer Immunotherapy, founded by Napster co-founder and former Facebook president Sean Parker, is a network of top institutions including Memorial Sloan Kettering, Stanford, MD Anderson Cancer Center and more.